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Updated: Jul 21, 2025

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
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Published on: December 22, 2020

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与癌症相关的纤维细胞通过外体环TBPL1介导的细胞间通信促进乳腺癌的进展

Fangzhou Ye1, Yiran Liang1, Yajie Wang1

  • 1Department of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, 250012, Jinan, Shandong, P. R. China.

Cell death & disease
|July 26, 2023
PubMed
概括

与癌症相关的纤维细胞 (CAF) 释放含有circTBPL1的外体,促进乳腺癌的进展. 这种外体环TBPL1通过调节miR-653-5p/TPBG通路来驱动瘤生长,提供了潜在的治疗点.

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