在原料中使用改性碳丝印刷电极对多克西环素的伏特度测定
M S Tiwari1, R G Thorat1, B B Popatkar1
1University Department of Chemistry, University of Mumbai, Santacruz (East), Mumbai, Maharashtra, 400 098, India.
概括
一个新的电化学传感器使用金和电化学减少的氧化石墨烯在印碳电极上检测抗生素多克西环林. 这种Au/ErGO/SPCE平台在食品和生物样本中提供高灵敏度和准确度的多西环林测定.
科学领域:
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
背景情况:
- 氧化石墨烯 (GO) 是一种用于电化学应用的多功能材料.
- 开发用于抗生素检测的敏感和选择性传感器对于公共卫生至关重要.
- 屏幕打印碳电极 (SPCE) 提供了一个具有成本效益和便携性的传感平台.
研究的目的:
- 开发一种新的电化学传感平台,用于对多西环林 (DC) 的敏感测定.
- 为增强电化学检测,合成和描述一个修改过的Au/ErGO/SPCE电极.
- 评估开发的传感器在食物和血清等复杂矩阵中的性能.
主要方法:
- 石墨烯氧化物使用修改后的汉默的方法制备和特征.
- 在印碳电极上制造了一个电化学传感平台Au/ErGO/SPCE.
- 电化学技术包括循环电压测量 (CV) 和正方波电压测量 (SWV) 用于DC检测和优化.
主要成果:
- 该Au/ErGO/SPCE显示出高灵敏度和准确度的多西环林检测.
- 优化的实验条件 (扫描速率,pH) 提高了DC的电化学反应.
- 传感器实现了0.124μM的检测极限 (LOD) 和0.415μM的量化极限 (LOQ) 的直流.
- 在真实样本 (如肉和血清) 中成功确定了低DC度.
结论:
- 开发的Au/ErGO/SPCE电化学传感器是准确和灵敏地确定多西环林的有希望的工具.
- 该平台显示了食品和制药行业质量控制应用的潜力.
- 电化学减少的氧化石墨烯和金纳米颗粒的整合提高了抗生素感应的电极性能.
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