一种微生物因果调解分析工具,用于健康差异和身体质量指数中的应用
Chan Wang1, Jiyoung Ahn2, Thaddeus Tarpey1
1Department of Population Health, Division of Biostatistics, New York University Grossman School of Medicine, New York, NY, 10016, USA.
新的SparseMCMM_HD框架分析了微生物组在健康差异中的调解作用,揭示了它在BMI等疾病中的重要作用. 微生物组简介的平衡可以将健康差异减少高达33%.
科学领域:
- 微生物组研究的研究.
- 在健康方面存在差异.
- 因果推理的原因推理.
背景情况:
- 人类微生物组在健康差异中的作用正在出现,但由于数据复杂性和不可操纵的暴露,缺乏分析框架.
- 现有的方法与微生物组数据的高维度,稀疏性和复合性作斗争.
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