在大洋洲的儿科炎性肠病的描述性流行病学:系统性审查和元分析
Angela J Forbes1, Chris M A Frampton1, Andrew S Day2
1From the Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand.
Journal of pediatric gastroenterology and nutrition
|July 27, 2023
概括
儿童炎症性肠病 (IBD) 在大洋洲越来越普遍,发病率和流行率很高,特别是在克罗恩病 (CD) 中. 对太平洋岛屿人口和土著群体需要进一步的研究.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 儿科健康 儿科健康
背景情况:
- 儿科炎症性肠病 (IBD) 是一种慢性,异常性胃肠道疾病,影响儿童的生活质量和医疗保健系统.
- 全球儿科IBD的发病率和患病率正在上升,需要区域流行病学数据.
研究的目的:
- 系统地审查和对大洋洲儿科IBD的发病率和流行率进行元分析.
- 描述该地区儿科克罗恩病 (CD) 和性结肠炎 (UC) 的当前流行病情景.
主要方法:
- 在2022年10月,对Medline,EMBASE和Web of Science数据库进行了系统的搜索.
- 使用随机效应模型计算了发生率和流行率的综合估计,其中包括来自澳大利亚和新西兰的研究.
- 数据收集包括各种方法,重点是19岁及以下的儿童.
主要成果:
- 十九篇文章产生了15个发病率和7个流行率研究,主要来自澳大利亚和新西兰.
- 每10万人/年的年均发病率是IBD4.1,CD2.3和UC0.9.
- 每10万人的综合流行率为IBD 36.0,CD 23.2和UC 7.6.
结论:
- 儿科IBD在大洋洲普遍存在,具有很高的发病率,特别是CD.
- 在澳大利亚土著,毛利族和新西兰太平洋儿童中观察到较低的IBD率.
- 太平洋岛国存在重大研究差距,突出了专门研究的必要性.
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