支持选择澳大利亚新的心血管风险方程的证据
Sinan Brown1, Emily Banks1, Mark Woodward2,3
1National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT.
The Medical journal of Australia
|July 27, 2023
概括
新西兰的PREDICT方程适用于澳大利亚心血管疾病 (CVD) 的初级预防. 它符合大多数CVD风险估计标准,有助于指导方针更新.
科学领域:
- 心血管健康 心血管健康
- 预防医学 预防医学
- 流行病学 流行病学
背景情况:
- 国际心血管疾病 (CVD) 初级预防指南建议各种风险方程.
- 评估这些方程对澳大利亚环境的适用性对于有效的心血管疾病风险管理至关重要.
- 澳大利亚国家心脏基金会委托进行此次审查,以告知指南更新.
研究的目的:
- 审查和评估国际CVD风险方程,以确定它们在澳大利亚的适用性.
- 根据预先定义的标准来评估用于初级预防的方程.
- 为2023年澳大利亚心血管疾病风险评估和管理指南的更新提供信息.
主要方法:
- 对十个国际CVD风险预测方程进行了系统审查.
- 方程根据八个选择标准进行评估,包括数据的同时性,风险因素的纳入,结果预测,人口代表性,模型性能和澳大利亚数据的外部验证.
- 还评估了在澳大利亚实际应用的可用性标准.
主要成果:
- 新西兰的PREDICT方程满足了八个选择标准中的七个.
- 这种方程也证明了在澳大利亚适用于实际应用的适用性.
- 其他经过审查的方程并不完全符合所需的标准.
结论:
- 新西兰的PREDICT方程是澳大利亚CVD初级预防指南中采用的强有力的候选者.
- 这项评估支持基于证据的建议,用于澳大利亚的CVD风险估计.
- 这些发现将有助于提高CVD风险评估工具的准确性和适用性.
相关概念视频
01:12Relative Risk
222
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
222
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
201
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
201
01:26Coronary Artery Disease IV: Preventive Measures
24
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
24
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
41
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
41
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
148
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148
01:30Coronary Artery Disease I: Introduction
21
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
21