从花果中快速提取生物活性化合物,使用新型可回收的深度环氧溶剂
Lijiao Wen1, Chen Fan1, Xi Zhao1
1Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, P. R. China.
Journal of separation science
|July 27, 2023
概括
深度环氧化溶剂提供了一种绿色替代品,用于从Gardenia jasminoides中提取生物活性化合物. 多德二甲基基氨酸化物-氨酸溶剂实现了高产量和可重复使用性,优于传统方法.
科学领域:
- 绿色化学 绿色化学
- 自然产品提取 提取自然产品
- 超分子化学 超分子化学
背景情况:
- 深度环氧溶剂 (DES) 正在成为传统有机溶剂的可持续替代品.
- 基于基化的DES被调查了它们在自然产品隔离中的潜力.
- 果 jasminoides Ellis是一种有价值的生物活性化合物的来源.
研究的目的:
- 开发和优化一个深度优化溶剂系统,以有效地从Gardenia jasminoides中提取生物活性化合物.
- 评估开发的DES用于天然产品提取的可重复使用性和可持续性.
- 为了比较优化DES的提取效率与传统方法.
主要方法:
- 使用响应表面方法来优化DES组成和提取参数.
- 使用多德二甲基基化和氨酸形成了DES.
- 在优化条件下进行了基尼化,基尼-1-β-d-gentiobioside,crocin-1和crocin-2的提取.
主要成果:
- 最佳的DES是二甲基二甲基基化物-氨酸 (1:3,mol/mol) 与35% (v/v) 的水.
- 优化的DES实现了目标化合物的总提取产量为70.6mg/g.
- 在第一个循环后,DES表现出高的可重复使用性,具有97.1%的持续提取效率.
结论:
- 基于二甲基二甲基基化物-氨酸的DES提供了一种高效,快速和绿色的方法,用于从Gardenia jasminoides中提取生物活性化合物.
- 开发的DES系统是可持续的和可重复使用的,在天然产品提取中为传统有机溶剂提供了一个有希望的替代品.
- 深层欧性溶剂显示出显著的潜力,作为可设计的溶剂,具有优越的提取能力,用于植物性材料.
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