益生菌发酵牛奶补充剂对行为和睡眠的影响
Samara M Freitas1, Beatriz Franco2, Giulio Saragiotto1
1School of Applied Sciences, University of Campinas, Limeira, Brazil.
Nutritional neuroscience
|July 27, 2023
概括
补充老鼠的益生菌Bifidobacterium animalis BB-12和石榴减少了焦虑和改善了睡眠效率. 睡眠不足影响了肠道微生物群,但Bifidobacterium水平保持稳定.
科学领域:
- 微生物学 微生物学
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 微生物群-肠-大脑轴影响行为和睡眠.
- 益生菌和特定的饮食成分可能会调节这个轴.
研究的目的:
- 为了研究用Bifidobacterium animalis BB-12和石榴果汁发酵的牛奶对老鼠行为,睡眠和肠道微生物群的影响.
- 评估睡眠不足对肠道微生物群的影响.
主要方法:
- 使用开放领域方法进行行为分析.
- 多睡眠学用于评估睡眠模式,包括REM睡眠剥夺.
- 便样本分析,以评估睡眠剥夺之前和之后的肠道微生物群组成.
主要成果:
- 补充剂减少了与焦虑相关的行为.
- 补充剂提高了睡眠效率,并在睡眠剥夺之前减少了觉醒.
- 睡眠不足减少了总细菌DNA,但Bifidobacterium属水平不受补充剂的影响.
结论:
- 用Bifidobacterium animalis BB-12和石榴发酵的牛奶显示出调节微生物群-肠-大脑轴的潜力.
- 这种干预措施对焦虑和睡眠质量产生了积极的影响.
- 肠道微生物群对睡眠不足很敏感,尽管Bifidobacterium种群似乎对这种特定干预有弹性.
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