评估过敏性鼻炎与中耳功能障碍之间的关联:临床病理学研究
Shaila Sidam1, Arshed M P2, Ujjawal Khurana3,3
1Otolaryngology - Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Cureus
|July 27, 2023
概括
这项研究发现,印度过敏性鼻炎患者的鼻腔细胞学和中耳问题之间没有联系. 大多数患者都有轻微的鼻腔症状和常见的耳部疾病,如尤斯塔希管功能障碍.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 细胞学 细胞学
背景情况:
- 过敏性鼻炎和中耳炎与输液 (OME) 之间的关系在印度还没有得到充分研究.
- 鼻腔细胞学,包括鼻涂抹中的绝对乙氨基酸计数 (AEC) 和乙氨基酸百分比,用于诊断过敏性鼻炎.
- 中耳功能障碍在过敏性鼻炎患者中很常见.
研究的目的:
- 评估鼻腔细胞学在过敏性鼻炎症状学中的作用.
- 在过敏性鼻炎患者中评估鼻腔细胞学和中耳功能障碍之间的关联.
主要方法:
- 进行了一项单一中心的,基于医院的观察性研究.
- 患有过敏性鼻炎症状的患者接受了耳鼻腔检查,包括鼻镜和耳鼻镜.
- 分析了鼻涂抹以检测埃索诺菲尔百分比,并确定了AEC.
- 在统计分析中使用了基二测试,在p < 0.05.05时具有显著性.
主要成果:
- 在126名过敏性鼻炎患者中,62名 (49.2%) 患有中耳功能障碍.
- 尤斯塔基管功能障碍 (ETD) 是最常见的中耳病理 (22%),其次是慢性中耳炎 (COM) (16.6%),OME (5.5%) 和急性中耳炎 (AOM) (4.5%).
- 中耳病理在10名绝对埃索诺菲利亚患者中的7名被发现.
结论:
- 鼻涂抹细胞学与鼻症状或中耳疾病的严重程度之间没有发现相关性.
- 打喷是最常见的鼻症状.
- 慢性中耳炎是观察到的最常见的中耳病理.
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