病例报告:青少年 CYP2D6 代谢较差的甲托克洛普拉米德诱导的急性反性反应

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Franz-Martin Fink1, Marta Bognar1, Petra Hengl1

  • 1Department of Pediatrics, Regional Hospital, St Johann in Tirol, Austria.

Frontiers in pharmacology
|July 27, 2023
PubMed
概括

梅托克洛普拉米德可能会引起急性 dystonic 反应,特别是在年轻人. 这项研究发现了两个青少年病例与CYP2D6低代谢器状态有关,这突出了处方前需要进行遗传测试的必要性.

关键词:
在CYP2D6中.剧烈的急性 dystonia 已经开始了.甲托克洛普拉米德的使用方法甲托克洛普拉米德诱导的急性 dystonic 反应药物遗传学 药物遗传学药物基因组学 药物基因组学这是一个很差的代谢器.

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