暴露于痴呆症与主观认知有什么关系? 一个系统的审查
Jennifer R Turner1,2, Nikki L Hill3, Leslie Brautigam3
1Edna Bennett Pierce Prevention Research Center, College of Health and Human Development, Pennsylvania State University, University Park, Pennsylvania, USA.
Innovation in aging
|July 27, 2023
概括
亲密接触痴呆症,特别是来自家庭或配偶,可能会增加主观认知衰退 (SCD) 报告. 然而,痴呆暴露和SCD之间的联系是不一致的,受到痴呆等因素的影响.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 心理学 心理学 心理学
背景情况:
- 主观认知衰退 (SCD) 可能在客观认知衰退之前发生.
- 除了认知表现之外的因素可以影响SCD.
- 痴呆症暴露和SCD之间的关联需要进一步调查.
研究的目的:
- 审查家庭病史或近亲非家庭接触痴呆症和自我报告的SCD之间的关联.
- 探索影响痴呆暴露和SCD之间的关系的修改因素.
主要方法:
- 在多个数据库 (PubMed,PsycINFO,Web of Science) 进行系统的文献搜索.
- 包括对社区成年人 (40+) 痴呆暴露和自我报告认知的研究.
- 使用LEGEND评估工具对证据和质量评估进行叙述综合.
主要成果:
- 收录了32篇文章,其中28篇文章质量良好.
- 痴呆症暴露和SCD之间的关系在研究中不一致.
- 六项研究发现了显著的关联,而17项没有发现,而9项报告了混合的结果.
结论:
- 痴呆症患者的第一级亲属和配偶可能会更频繁地报告SCD.
- 痴呆症暴露和SCD影响结果的定义中的异质性.
- 未来的研究应该调查像暴露的感知意义这样的修饰因素,以增强早期干预策略.
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