甲状腺状乳腺癌:一个病例报告和文学综合审查
Abdel Mouhaymen Missaoui1,2, Fatma Hamza2,3, Wafa Belabed1,2
1Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia.
Frontiers in endocrinology
|July 27, 2023
概括
甲状腺小胞状甲状腺癌 (WLPTC) 是一种罕见的甲状腺癌亚型. 这项研究回顾了150例病例,发现它经常出现部胀和有利的结果,类似于经典的乳头甲状腺癌.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 乳头甲状腺癌 (PTC) 是最常见的内分泌恶性瘤.
- 甲状腺小胞状甲状腺癌 (WLPTC) 是一种不常见的,独特的PTC亚型.
- 本报告详细介绍了一个新的WLPTC案例,并回顾了现有的文献.
研究的目的:
- 为了呈现一种独特的Worthin-like papillary thyroid carcinoma (WLPTC) 病例. 这是一个独特的病例.
- 对WLPTC的临床,病理和治疗方面进行全面的文献审查.
- 为了更广泛的理解,将150个WLPTC案件的数据整合起来.
主要方法:
- 在PubMed和谷歌学者 (1995-2022) 上进行了文献搜索.
- 在最初审查的148篇文章中,选出了25篇相关文章 (13篇案例报告,12篇案例系列).
- 数据提取的重点是临床表现,成像,组织学,管理和结果.
主要成果:
- 一名27岁的女性出现部胀,诊断出双焦PTC包括WLPTC和慢性淋巴细胞甲状腺炎 (CLT).
- 对150例WLPTC病例的文献审查显示,平均年龄为39岁,女性占主导地位,并经常出现部胀.
- 71.6%的人有阳性甲状腺自身免疫;28%的人有淋巴结转移,总体结果有利.
结论:
- WLPTC表现出与经典PTC类似的临床和放射性特征.
- 组织学特征包括瘤细胞,乳头核变化和淋巴状层瘤,通常与相关的CLT有关.
- 管理与经典的PTC保持一致,产生可比,有利的结果.
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