[阻塞性睡眠呼吸暂停-呼吸暂停综合征中的夜间血压波动]
María Jesús Pablo Zaro1, Isabel Benavente Aguilar1, Yolanda Lasierra Périz1
1Unidad de Sueño, Hospital General San Jorge, Huesca, España.
Open respiratory archives
|July 27, 2023
概括
患有睡眠呼吸暂停/睡眠暂停综合征的患者在睡眠期间经历静脉压升高,面临心血管风险增加,特别是患有动脉高血压的患者. 这种风险与发展并发病症有关,需要新的治疗方法.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 高血压研究 高血压研究
背景情况:
- 睡眠呼吸暂停/呼吸暂停综合征与心血管风险有关.
- 动脉高血压 (HT) 是已知的心血管风险增加的标志物.
- 睡眠期间静脉压升高可能表明心血管风险增加.
研究的目的:
- 为了确定睡眠呼吸暂停/低血压综合征和睡眠期间静脉压升高的患者是否有较高的心血管风险,当动脉高血压存在与非高血压患者相比.
- 为了研究睡眠期间心压升高,动脉高血压和睡眠呼吸暂停/睡眠暂停综合征患者心血管风险之间的关联.
主要方法:
- 一项前性研究分析了102名睡眠呼吸暂停/睡眠暂停综合征患者 (64名高血压患者,38名非高血压患者) 的生物识别和多睡眠识别参数.
- 参数包括呼吸暂停-呼吸暂停指数 (AHI),氧气不和,兴奋指数,睡眠阶段,并发症和治疗方法.
- 从2013-2017年和2020年间的多睡眠学研究中收集的数据.
主要成果:
- 在高血压和非高血压组之间没有发现生物识别或多睡眠学参数的统计学上显著差异.
- 在随访期间,高血压组的并发症在随访期间更频繁地发展.
- 高血压组的患者需要更频繁地接受新的治疗.
结论:
- 睡眠期间静脉压升高意味着睡眠呼吸暂停综合征和动脉高血压患者心血管风险增加,主要是由于相关的并发症.
- 在患有睡眠呼吸暂停综合征的非高血压个体中,睡眠期间静脉压升高也可能表明与孤立阻塞性睡眠呼吸暂停相比,血管并发症的风险增加.
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