在英格兰从2000年到2019年的慢性阻塞性肺病的患病率
Philip W Stone1, Michael Osen2, Andrew Ellis2
1National Heart and Lung Institute/School of Public Health, Imperial College London, London, UK.
概括
在英格兰,慢性阻塞性肺病 (COPD) 的患病率从2000年至2019年增加. 常见的定义可能低估了COPD的真实患病率,这可能会影响医疗保健资源分配.
科学领域:
- 肺部医学 肺部医学
- 医疗信息学 医疗信息学
- 流行病学 流行病学
背景情况:
- 国际估计慢性阻塞性肺病 (COPD) 患病率因不同病例定义而有很大差异.
- 准确的COPD流行数据对于有效的医疗保健资源分配至关重要.
- 十多年来,英国的COPD患病率估计没有更新,因此需要进行当前的研究.
研究的目的:
- 计算2000年至2019年英格兰每年COPD患病率.
- 为了比较来自五个不同的COPD定义的患病率估计.
- 分析20年COPD患病率的趋势.
主要方法:
- 使用了来自临床实践研究数据链接 (CPRD) Aurum数据库的电子医疗记录 (EHR) 数据.
- 综合二级护理数据来自医院病例统计 (HES) 入院患者护理 (APC) 数据库.
- 在40岁以上的成年人中计算了年中患病率,使用了五个定义,包括验证病例,质量和结果框架 (QOF) 代码,基于症状的标准和住院记录.
主要成果:
- 超过1270万个人在20年内被纳入,年度队列规模从2000年的430多万增加到2019年的610多万.
- 据估计,COPD的患病率从2000年到2019年每年都在持续增加.
- 在2019年,验证的COPD患病率为4.9% (定义1或5),当包含潜在未被诊断的病例时,患病率上升至6.7% (定义3).
结论:
- 标准定义,如质量和成果框架 (QOF) 代码,可能大大低估了COPD的真实患病率.
- 随着时间的推移,估计和实际患病率之间的差距越来越大,可能导致资源分配不足.
- 在EHR中标准化COPD编码,并纳入诸如螺旋计等指标,对于精确的疾病监测至关重要.
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