神经退行症的言语和语言标志物:呼吁全球公平
Adolfo M García1,2,3,4, Jessica de Leon5, Boon Lead Tee1,5
1Global Brain Health Institute, University of California, San Francisco, CA 94143, USA.
Brain : a journal of neurology
|July 27, 2023
概括
语音和语言评估有助于诊断神经退行. 跨语言研究对于公平的大脑健康标志物至关重要,它解决了当前研究中对英语的偏见.
科学领域:
- 神经科学是一个神经科学.
- 语言学的语言学.
- 神经学 神经学
背景情况:
- 语音和语言评估对于诊断神经退行性疾病如阿尔茨海默病,帕金森病和前性痴呆症至关重要.
- 数字工具提供可扩展的,低成本的方法来检测语音异常,潜在地创造公平的大脑健康标志物.
- 目前的研究和临床工具的语言多样性有限,主要集中在英语使用者身上.
研究的目的:
- 倡导跨语言研究作为解决神经退行研究中语言不平等问题的策略.
- 审查语言评估在主要神经退行性疾病中的作用.
- 突出语言对神经退行症语言功能障碍的影响以及以英语为中心的基准标准的局限性.
主要方法:
- 在初级渐进性失言症和常见的神经退行性疾病中调查语言评估的使用情况.
- 分析语言不公平,包括忽视大多数全球语言,依赖英语群体.
- 审查关于神经退行性疾病的语言特异性变异和英语作为通用基准不足的研究.
主要成果:
- 神经退行性疾病中的语言功能障碍可能是语言依赖的.
- 英语发言人代表了一个低于最佳的基准来评估不同语言群体中神经退行性疾病.
- 由于世界上大多数语言在科学文献中的代表性不足,存在重大不平等.
结论:
- 跨语言研究对于开发全球平等的脑健康标志物至关重要.
- 解决语言偏见对于推动全球神经退行性疾病的准确诊断和表征至关重要.
- 实施跨语言方法需要克服工具开发和研究倡议方面的挑战.
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