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通过接种疫苗,可能减少SARS-CoV-2症状的急性后续症状

Greg Vanichkachorn¹, Elizabeth Gilman¹, Ravindra Ganesh¹

¹Mayo Clinic, Rochester, MN, USA.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research

|July 27, 2023

概括

接种COVID-19疫苗可能会减少COVID后疾病 (PCC) 症状. 接种疫苗的人报告PCC症状较少,包括腹痛,胸痛和呼吸不全,表明功能改善.

科学领域:

免疫学免疫学免疫学
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

后COVID状况 (PCC) 是一个重大的公共卫生挑战.
了解影响PCC症状严重程度的因素对于患者管理至关重要.
疫苗接种对PCC临床表现的影响需要进一步调查.

研究的目的:

调查重症急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 疫苗接种是否会改变COVID后疾病 (PCC) 的临床表现.
评估COVID-19感染前的疫苗接种状态与PCC症状的流行率和严重程度之间的关系.

主要方法:

观察性研究分析了477名在梅奥诊所寻求PCC护理的患者的自我报告数据.
接种疫苗 (n=245) 和未接种疫苗的受试者之间报告症状的比较.
统计分析,包括邦费罗尼校正,以确定症状表现的显著差异.

主要成果:

接种PCC疫苗的受试者报告了症状的发生率较低,包括腹痛,厌氧,,胸痛,头,麻木/刺痛,呼吸不全,虚弱和.
在患有PCC的住院患者中,接种疫苗与胸痛,咳,头和呼吸障碍的报告减少有关.
减少腹痛在邦费罗尼校正后仍然是一个统计学上显著的发现.

结论:

接种SARS-CoV-2疫苗可能会减轻与COVID后条件相关的症状的严重程度和范围.
接种疫苗可能会导致患有PCC的个体改善患者的发病率和功能结果.
需要进一步的研究来阐明疫苗接种对PCC恢复的机制和长期影响.

关键词:

在 COVID-19 疫情中,在SARS-CoV-2的后急性后果.长途COVID的长途旅行流行病是一种流行病.接种疫苗接种疫苗

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