微流体集成多模式可穿戴混合补丁用于无线和持续生理监测
Md Abu Zahed1,2, Dong Kyun Kim1,2, Seong Hoon Jeong1,2
1Department of Electronic Engineering, Kwangwoon University, 447-1, Seoul 139-701, Republic of Korea.
ACS sensors
|July 27, 2023
概括
本研究介绍了一种可穿戴的贴片,用于实时无线监测葡萄糖和心电图 (ECG),使用集成的微流体生物传感器和灵活的材料来提高运动期间的准确性.
科学领域:
- 生物医学工程 生物医学工程
- 可穿戴技术可穿戴技术
- 生物感应是一种生物感应.
背景情况:
- 现有的可穿戴系统往往缺乏微流体集成,小型化和多模式性.
- 需要先进的可穿戴设备,能够进行持续的实时生理监测.
研究的目的:
- 设计和制造一个灵活的,基于补丁的无线系统,将多式生物传感 (生物化学和电生理学) 与微流体通道集成在一起.
- 为了实现精确的,实时的,持续的汗水葡萄糖和心电图 (ECG) 的监测.
主要方法:
- 制造基于氧化石墨烯的微流体葡萄糖生物传感器和基于MXene-polyvinylidene化物的干电图电极.
- 传感器集成到一个灵活的补丁,用于无线数据传输.
- 使用运动期间人类受试者的汗水样本进行验证,并实时调整pH值和温度.
主要成果:
- 葡萄糖生物传感器显示出高灵敏度 (19.97 μA mM-1 cm-2) 和稳定性.
- 干电图电极表现出低阻抗 (40.5 kΩ cm2) 和高的信号噪声比率 (23.432.8 dB).
- 该系统成功地在体力活动期间无线和实时监测出汗葡萄糖和心电图.
结论:
- 开发的多式联动可穿戴系统为持续的生理监测提供了更好的可穿戴性和易用性.
- 微流体和多式传感器的整合通过补偿环境因素来提高准确性.
- 这项技术有望用于先进的健康监测应用,特别是在体力运动期间.
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