在欧盟/欧洲经济区/英国国家/地区的一般人口和关键风险群体中估计的乙型肝炎病毒流行率:系统性审查
Sandra Bivegete1,2, Anna L McNaughton1, Adam Trickey1
1Population Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
概括
慢性乙型肝炎病毒 (HBV) 的流行率在欧洲仍然很低.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 慢性乙型肝炎病毒 (HBV) 负担在欧盟 (EU) 和欧洲经济区 (EEA) 国家之间存在差异.
- 以前的HBV流行率估计可用于2005年至2017年.
研究的目的:
- 更新2018-2021年欧盟/欧洲经济区国家和英国的HBV流行率估计.
- 在各种风险人群中确定HBV流行趋势.
主要方法:
- 综合现有HBV流行数据库的系统审查 (2005年至2017年).
- 搜索了有关HBV表面抗原在一般人群,孕妇,首次献血者 (FTB),与男性发生性关系的男性 (MSM),移民和被监禁者的英语文章.
- 包括来自国家专家的灰色文献数据和评估偏差风险.
主要成果:
- 增加了147个新的流行率估计 (总数n=579).
- 在一般人群中,乙型肝炎病毒的平均患病率为0.5%,在希腊 (3.8%) 最高.
- 在特定群体中观察到的患病率最高:FTB (立陶宛,0.8%),孕妇 (罗马尼亚/意大利,5.1%),移民 (西班牙,31.7%),MSM (克罗地亚,3.4%) 和监狱人员 (希腊,8.3%).
- 与2017年相比,孕妇的中位患病率下降了 (0.3%),但在移民 (5.8%) 和监狱人员 (2.1%) 中增加了.
结论:
- 在欧洲一般人口中,HBV的患病率一般较低.
- 患病率集中在特定的风险群体内,包括移民和被监禁的人.
- 对于这些高风险人群,建议针对性查和治疗策略.
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