作为1年预后因素的初始功能性残疾是住院治疗SARS-CoV-2感染的老年患者的预后因素
Olivier Brière1, Marie Otekpo1, Marine Asfar1
1Department of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France.
住院时的功能障碍显著增加了老年COVID-19患者的死亡风险. 功能能力得分较低的脆弱老年人在一年内面临更差的生存结果.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19不成比例地影响老年人,需要调整临床实践.
- 初始功能能力是老年患者的关键预后指标,特别是在感染期间.
研究的目的:
- 为了评估基线功能残疾和1年死亡风险之间的关联在老年人住院治疗COVID-19的老年人.
主要方法:
- 一项纵向研究包括97名因COVID-19住院的老年患者.
- 在入院时使用组异源 (GIR) 评分来评估功能性残疾 (残疾定义为GIR ≤3).
- 一年后收集了死亡率数据,并根据年龄,性别,并发症和治疗进行了调整.
主要成果:
- 46.4%的参与者在基线时GIR得分≤3.
- 一个GIR得分≤3与1年死亡率增加2.27倍的风险显著相关.
- 具有GIR得分≤3的患者的生存时间显著缩短 (日志排名P = 0.0029).
结论:
- 最初的功能障碍是住院老年COVID-19患者生存率较差的强有力的预测因素.
- GIR得分可以识别患有COVID-19后住院死亡风险较高的脆弱老年人.
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