在跨导管大动脉置换 (TAVR) 程序中,ProGlide 与 Prostar 的血管并发症:元分析
Yuwei Xiang1, Chen Chen2, Jichun Zhao1
1Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.
BJS open
|July 27, 2023
概括
普罗格莱德在输血管穿管大动脉置换方面表现出比普罗斯塔尔更高的安全性和有效性,显示出较少的主要血管并发症和器件故障. 这一分析突出了ProGlide的优势.
科学领域:
- 心血管干预 心血管干预
- 医疗器械技术 医疗器械技术
- 血管外科 血管外科
背景情况:
- 皮肤输血穿透导管大动脉置换 (TAVR) 需要有效的血管闭塞装置.
- 比较ProGlide和Prostar关闭装置的安全性和有效性对于优化TAVR程序至关重要.
研究的目的:
- 进行一项元分析,比较与ProGlide与Prostar相关的血管并发症,用于皮肤输血膜TAVR.
- 评估初级 (主要的血管并发症) 和二次结果,包括轻微的并发症,设备故障和需要额外的干预措施.
主要方法:
- 电子数据库的系统文献搜索到2022年7月.
- 包括9项研究,包括7529名患者 (4144名ProGlide,3385名Prostar).
- 随机效应元分析以计算汇集的几率比率 (OR) 和95%置信区间 (CI);在非随机研究中偏差的风险 - 干预 (ROBINS-I) 偏差评估工具.
主要成果:
- 与Prostar相比,ProGlide显著降低了主要血管并发症 (OR 0.50) 和设备故障 (OR 0.45) 的风险.
- 虽然血管创伤率相似,但ProGlide显示出较低的出血风险 (OR 0.46),但较高的缺血风险 (OR 1.90).
- 普罗格莱德的使用与手术治疗较少 (OR0.52),但更多的内血管治疗 (OR2.69) 与并发症有关.
结论:
- 与Prostar相比,ProGlide在皮肤输血管TAVR中提供了更高的安全性和有效性,主要血管并发症和设备故障率较低.
- 用ProGlide治疗的血管并发症通常通过内血管方法而不是手术来治疗.
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