阴道EEG:老年人的病因和死亡率与非状态发作
1Postgraduate Program in Health Sciences, Pontifícia Universidade Católica de Campinas, Campinas, SP, Brasil.
Clinical EEG and neuroscience
|July 27, 2023
概括
在老年人中,非性状态 (NCSE) 通常呈现为焦点NCSE与意识受损. 对NCSE的良好预后与初始治疗反应和特定的EEG发现有关.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 在老年人中确定非性状态 (NCSE) 亚型的临床,病因和预后数据仍然是一个挑战.
- 老年人代表了一个脆弱的人群,NCSE可以在其中独特地表现出来.
研究的目的:
- 评估诊断为NCSE的老年人的临床半学,脑电图 (EEG) 发现和预后指标.
- 在老年人群中描述NCSE亚型.
主要方法:
- 一项涉及老年人进入急诊室时意识发生改变的前性研究.
- 收集和分析了临床和EEG数据,用于NCSE诊断和亚型.
- 评估了病因,治疗反应和30天死亡率.
主要成果:
- 在105名老年人中,47.6%的人 (平均年龄为72.8岁) 诊断出NCSE.
- 结构性病因是最常见的 (82%). 脑电图显示68%的患者出现了形放电 (EDs>2.5 Hz),70%的患者出现了节律三角形活动/横向周期性模式.
- 最初的临床改善发生在36例病例中,但30天死亡率为38.8%. 良好的预后与初始治疗反应和EDs>2.5Hz的EEG相关.
结论:
- 焦点NCSE与意识受损是老年人中最常见的亚型.
- 虽然初始治疗可能会导致改善,但整体死亡率仍然很高.
- 早期的临床改善和特定的EEG发现 (ED>2.5Hz) 与老年NCSE患者的更好的预后有关.
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