通过基于吸附辅助异构化和同时净化的一种集成的一玻利酸亲和吸附剂的高纯度乳糖的生产
Mingming Wang1, Lu Wang2, Xiao Hua2
1College of Food Science and Engineering, Ocean University of China, Qingdao, Shangdong Province 266003, China; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province 214122, China.
Food chemistry
|July 27, 2023
概括
这项研究提出了一种新的方法,使用酸亲和染色法生产高纯度乳糖. 该工艺实现了高产量和纯度,为乳糖生产提供了可持续的途径.
科学领域:
- 碳水化合物化学 碳水化合物化学
- 分离科学 分离科学
- 生物技术是生物技术.
背景情况:
- 高纯度乳糖对于医疗和食品应用至关重要.
- 目前的合成方法在实现高产量和纯度方面面临挑战.
- 乳糖的高效和可持续生产仍然是一个重要的目标.
研究的目的:
- 开发一种高效的实验室规模战略,用于合成高纯度乳糖.
- 在一个单一的过程中,将乳糖到乳糖的异构化与同时回收相结合.
- 为高纯度乳糖建立可持续的生产方法.
主要方法:
- 使用酸亲和吸附剂包装的柱子用于并发的异构化和恢复.
- 采用吸附辅助的乳糖到乳糖的异体化.
- 实现了乳糖回收的顺序脱.
主要成果:
- 实现了高达80.20%的乳糖产量增强,副产品产量低 (6.30%).
- 恢复了90%以上的吸附乳糖,其纯度超过98%.
- 获得高纯度乳糖的净产量高达72.31%,这是一个报告的记录.
结论:
- 开发的战略为高纯度乳糖生产提供了一种高效和可持续的方法.
- 装有酸亲和吸附剂的柱子表现出了卓越的操作稳定性.
- 这种方法对工业规模的可持续乳糖合成具有重大潜力.
相关概念视频
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Overview
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
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