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Updated: Jul 21, 2025

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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PCSK9参与自闭症病因:序列变异,蛋白质度和促进物甲基化

Sohair Salem1, Rehab Mosaad1, Randa Lotfy1

  • 1Molecular Genetics and Enzymology Department, Human Genetics and Genome Research Institute, National Research Centre, Cairo, Egypt.

Archives of medical research
|July 27, 2023
PubMed
概括

这项研究表明,Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) 可能与自闭症有关. 在患有自闭症的个体中观察到高PCSK9蛋白水平和改变的基因促进物甲基化.

关键词:
自闭症 自闭症 自闭症PCSK9, 序列变化, 血蛋白度, 甲基化

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