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在膀癌中与过度活跃的膀类症状相关的因素
Masahiro Tachibana1, Kazuna Tsubouchi1, Yuichiro Fukuhara1
1Department of Urology, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
Anticancer research
|July 27, 2023
概括
膀癌患者的过度活动膀症状,如频繁排尿和急需排尿,与瘤特征有关. 在位癌 (CIS) 与频繁排尿有关,而较大的瘤与急迫性和失禁相关.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
背景情况:
- 过度活跃的膀 (OAB) 症状可能会影响患有膀癌的患者.
- 调查膀癌和OAB类症状之间的关系对于患者管理至关重要.
研究的目的:
- 在被诊断为膀癌的患者中探索与过度活性膀 (OAB) 类似症状相关的因素.
- 为了确定可能引发OAB类症状的膀癌的特定特征.
主要方法:
- 这项研究包括59名接受过尿道切除膀瘤 (TURBT) 的患者.
- 使用过度活性膀症状评分 (OABSS) 和国际前列腺症状评分 (IPSS) 问卷来评估类似于OAB的症状.
- 关键的结果集中在识别引起这些症状的膀癌相关因素.
主要成果:
- 50名患者患有非肌肉侵入性膀癌 (NMIBC),其中14人患有现场癌 (CIS).
- 波拉基苏里亚 (频繁排尿) 在NMIBC患有CIS的患者中明显高于没有CIS的患者 (p=0.02).
- 瘤直径与急性 (p=0.01) 和急性失禁 (p=0.03) 有显著的相关性.
- 多变量分析证实CIS与波拉基苏里 (p=0.02) 和瘤大小与急性和失禁相关 (p=0.04,p=0.01).
结论:
- 在非肌肉侵袭性膀癌 (NMIBC) 中的本位癌 (CIS) 与频繁排尿有关.
- 较大的膀瘤直径与急迫性和急迫性失禁的增加有关.
- 在膀癌患者中存在波拉基苏里亚可能表明CIS.
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