[翻译文章] 关于碳烯和人环素的变化是否已纳入?
Susana Redondo Capafons1, Laura Soriano Gutierrez1, Elsa Dalmau Portulas2
1Servicio de Farmacia Hospitalaria, Corporació Sanitària Parc Taulí, Sabadell, Spain.
概括
这项研究发现,尼图平坦/帕洛诺塞 (NEPA) 与德克萨米他 (NEPAd) 是一种具有成本效益的抗emetic选择,显示与其他疗法治疗化疗诱导的恶心和吐类似的有效性. 使用NEPAd可以节省大量的成本.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
背景情况:
- 目前的MASCC/ESMO指导方针 (2016) 建议对高排泄性化疗 (HEC) 和碳柏金进行三重抗治疗.
- 这些指导方针将环素方案纳入HEC,并主张三重疗法来管理急性和延迟吐.
研究的目的:
- 评估MASCC/ESMO指导方针与化疗门诊病房中的实际抗预防的一致性.
- 评估处方抗疗法的有效性.
- 为了确定使用口服网皮坦/帕洛诺塞 (NEPA) 与静脉注射 (IV) 德甲 (NEPAd) 的成本节约,而不是使用IV 普雷皮坦与丹塞和德甲 (FOD IV) 的成本节约.
主要方法:
- 进行了一项前性观察性研究,收集了患者人口统计,化疗方案, emetogenic 风险和 antiemetic 方案的数据.
- 使用MASCC调查,救援药物使用和紧急访问/住院治疗来评估有效性.
- 进行了成本最小化药物经济分析.
主要成果:
- 包括61名患者;21.1%的抗疗方案与MASCC/ESMO建议不一致.
- 报告的高效率为:急性恶心的90.9%,急性吐和延迟恶心的100%,延迟吐的72.7%.
- 救援药物的使用从第一期的18.7%下降到第二期没有;没有紧急访问或住院治疗.
结论:
- 与FOD IV相比,NEPAd的成本降低了28%,这表明它是一种有效的抗选择.
- 在临床实践和MASCC/ESMO指南之间观察到很高的一致性.
- 在临床实践中,NEPAd和FOD IV似乎在治疗化疗引起的恶心和吐方面具有相似的有效性.
关键词:
这是一种反,反.化疗 化疗是一种化学疗法.一致性 一致性 一致性一致性协作 (Concordancia) 是一个协作.费用 费用 费用 费用 费用 费用 费用这就是Coste Coste的价格.有效性的效果.有效性 有效性.准则 准则 准则 准则导游指南 (Guías Guías) 是一个指南.化疗是一种化学疗法.更多相关视频
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