交付时间因素对治疗时间和图形疗法计划质量的影响
Takayuki Yagihashi1,2, Tatsuya Inoue3,4, Shintaro Shiba5
1Department of Medical Physics, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-8533, Japan.
Scientific reports
|July 27, 2023
概括
在断层疗法规划中的交付时间因子 (DTF) 显著影响治疗效率和计划质量. 优化DTF可以提高计划质量,但持续增加导致更长的治疗时间.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 放射治疗技术 放射治疗技术
背景情况:
- 雷Station治疗计划系统引入了对断层治疗的交付时间因子 (DTF).
- 了解DTF对治疗效率和计划质量的影响,对于优化放射治疗至关重要.
研究的目的:
- 调查交付时间因子 (DTF) 对断层疗法治疗计划的影响.
- 评估不同的DTF对不同癌症部位的交付效率和计划质量的影响.
主要方法:
- 包括25名头癌,肺癌和前列腺癌患者.
- 螺旋式断层疗法计划被创建并重新计算,DTF范围从1.0到3.0.
- 分析了治疗时间,调制因子,符合性指数,同质性指数和风险器官剂量.
主要成果:
- 治疗时间和调制因子随着DTF增加而单调地增加,每0.1 DTF增量增加约10%
- 计划质量指数 (CI,同质性,OAR剂量) 通常在较高的DTF下得到改善,但肺癌CI除外.
- 计划质量的改善在某些DTF值处停滞不前,而治疗时间继续增加.
结论:
- 交付时间因子 (DTF) 是提高断层疗法计划质量的关键参数.
- 在选择最佳的DTF时,平衡治疗时间和计划质量至关重要.
- DTF优化为图解疗法中改善放射治疗结果提供了一条途径.
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