果心脏和运动研究的33080名参与者的脉冲氧计值
Ian Shapiro1, Jeff Stein1, Calum MacRae2,3
1Apple Inc., Cupertino, CA, USA.
NPJ digital medicine
|July 27, 2023
概括
穿戴式脉冲氧计 (SpO2) 设备从超过33,000人中捕获了7200万个读数. 分析揭示了健康的昼夜氧和模式,并确定了SpO2趋势的人口变化.
科学领域:
- 生理学 生理学 生理学
- 生物医学工程 生物医学工程
- 数字健康数字健康
背景情况:
- 可穿戴设备为大规模的生理数据收集提供了新的机会.
- 脉冲氧计 (SpO2) 测量可以通过非侵入性方法获得.
- 了解不同人群中的SpO2变化对于建立健康基准至关重要.
研究的目的:
- 分析来自可穿戴设备的SpO2测量的大量数据集.
- 在自然条件下建立 SpO2 的人口水平参考趋势.
- 调查对 SpO2 昼夜模式和趋势的人口影响.
主要方法:
- 在果心脏和运动研究中的33,080名参与者的7200万个SpO2值的横截面分析.
- 按年龄,性别,BMI,家庭高度和种族/种族分层.
- 多变量普通最小平方回归用于量化人口水平趋势.
主要成果:
- 在所有人口群体中,SpO2测量显示出一致的昼夜模式,夜间和率较低.
- 日间SpO2回归系数与基于实验室的参考模型保持一致.
- 在性别之间观察到年龄和BMI依赖的SpO2趋势的显著差异.
- 在种族/民族群体中,在白天的SpO2中发现了小而统计上显著的差异.
结论:
- 可穿戴的SpO2设备可以在临床环境之外建立健康人口的参考趋势.
- 循环 SpO2 模式在人口统计学中强大,但年龄,性别和BMI 影响趋势.
- 进一步的研究可以根据个体人口因素来完善SPO2的解释.
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