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影响通道的子毒素表现出双 cis-trans 异构体

Konstantin S Mineev1, Mikhail A Chernykh1, Vladislav V Motov1,2

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

FEBS letters
|July 28, 2023
PubMed
概括

子α-毒素 (alpha-NaTx) 是阻断通道的小蛋白质. 这项研究表明,由于独特的键配置,Lqq4毒素采用多种结构,扩大了已知的α-毒素的构造空间.

关键词:
这是一种cis-peptide键.神经毒素是一种神经毒素.核磁共振是一种核磁共振.蛋白质结构 蛋白质结构毒药是一种毒药.电压门式通道的通道.

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