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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Development of Immunocompetence01:22

Development of Immunocompetence

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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相关实验视频

Updated: Jul 21, 2025

An Ex vivo Culture System to Study Thyroid Development
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一个具有先天性低甲状腺症的新生儿的大型甲状腺:甲状腺体大小减少的时间表.

Kaitlin July O'Brien1,2, John J Ceremsak1, Jean-Nicolas Gallant1

  • 1Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Ear, nose, & throat journal
|July 28, 2023
PubMed
概括
此摘要是机器生成的。

遗传性甲状腺功能低下症可能会导致新生儿的大肠. 及时的甲状腺激素替代导致了显著的回归,避免了手术并确保了正常发育.

关键词:
航空消化压缩压缩.遗传性甲状腺功能低下症是先天的生产性子质量 子质量内分泌手术是指内分泌手术.甲状腺囊是什么?甲状腺囊是什么?

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科学领域:

  • 新生儿医学 新生儿医学
  • 儿科内分泌学 儿科内分泌学
  • 医疗成像医学成像

背景情况:

  • 在新生儿中,先天性甲状腺功能低下症 (CH) 很少表现为显著的部质量.
  • 一个大的胎儿子会导致气道阻塞,需要剖腹产.
  • 部质量的产前诊断需要仔细评估潜在的疾病,如CH.

研究的目的:

  • 报告一个先天性甲状腺功能低下症的病例,呈现出大囊.
  • 讨论胎儿和新生儿部质量的成像方法.
  • 审查新生儿二次性子的医疗和外科治疗策略.

主要方法:

  • 产前超声波检查发现一个大中线部质量.
  • 带切显示了甲状腺刺激激素 (TSH) 的升高.
  • 产后核磁共振扫描 (MRI) 证实了大子;通过实验室研究确立了初级甲状腺功能低下症的诊断.

主要成果:

  • 婴儿被诊断出患有先天性甲状腺功能低下症和大囊.
  • 用levothyroxine的治疗在几周内显著减少了子体积.
  • 婴儿没有持续的压缩症状,并表现出正常的生长和神经发育.

结论:

  • 早期诊断和使用甲状腺激素替代的治疗对于回归至关重要.
  • 医疗管理往往可以防止需要手术干预的新生儿由于CH.
  • 尽管最佳的医疗治疗,但持续压缩症状的病例保留了外科考虑.