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Updated: Jul 21, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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在多发性骨髓瘤中,T细胞重定向双特异性和三特异性抗体,超出BCMA

Niels W C J van de Donk1,2, Chloe O'Neill1,2, Maaike E M de Ruijter1,2

  • 1Department of Hematology, Amsterdam UMC, location Vrije Universiteit Amsterdam.

Current opinion in oncology
|July 28, 2023
PubMed
概括

新的T细胞疗法,包括针对新型抗原的双特异性抗体,如GPRC5D和FcRH5,对在BCMA导向治疗中进展的多发性骨髓瘤患者有希望. 进一步的研究正在探索组合策略和三种特异性抗体以改善结果.

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