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Updated: Jul 21, 2025

Author Spotlight: Fluorescence-Based Quantification of Mitochondrial Membrane Potential and Superoxide Levels Using Live Imaging in HeLa Cells
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UBQLN2和HSP70通过促进外层线粒体膜破裂,参与帕金因介导的线粒体衰变

Qilian Ma1,2, Jiaqi Xin1, Qiang Peng1

  • 1Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, China.

EMBO reports
|July 28, 2023
PubMed
概括

乌比基林2 (UBQLN2) 蛋白质对于通过线粒细胞衰变来清除受损的线粒体至关重要. UBQLN2中的突变损害了这一过程,将髓功能障碍与ALS和FTD等神经退行性疾病联系起来.

关键词:
这就是ALS.停车场可以停车.UBQLN2 的时间.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.在任何地方都是无处不在的.

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