无对比心脏计算机断层扫描衍生中位膜环状化得分在中位膜疾病中
Jie Hou1,2,3, Yu Sun1,2,3, Huishan Wang4
1College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, Liaoning, China.
Clinical cardiology
|July 28, 2023
概括
心脏CT的定量额外环状化 (MAC) 评分预测了额外膜疾病 (MVD) 患者手术内转换和心律失常的风险更高,有助于手术规划和患者管理.
科学领域:
- 心血管成像 - 心血管成像
- 心脏外科手术 心脏外科手术
- 膜心脏疾病 膜心脏疾病
背景情况:
- 通过计算机断层扫描 (CT) 检测到的中枢环状化 (MAC) 是已知的不良结果的预测因素.
- 量化MAC参数的预后价值在管理中关膜疾病 (MVD) 仍在调查中.
研究的目的:
- 评估从MVD患者的非对比心脏CT中获得的定量MAC得分的预后意义.
- 为了确定MAC分数是否能改善手术内转换和术后心律失常的风险分层.
主要方法:
- 预期招募300名MVD患者 (80名有MAC,220名没有) 接受手术前的心脏CT和心交门手术.
- 无对比心脏CT用于MAC检测和评分.
- 收集的数据包括基线临床因素,手术内转化率和随访心律失常数据.
主要成果:
- 患有MAC的患者年龄较大,女性更频繁,并且有较高的大动脉结石化率,心脏狭窄和心房动.
- 患有MAC的患者表现出显著更高的额头置换率和手术内转换率.
- 马克分数独立地预测了手术内转换,而马克分数和左心房末端透气维度预测了后续心律失常.
结论:
- 来自非对比心脏CT的定量MAC得分是MVD患者不良事件的有价值预测指标.
- 这些得分可以识别患有术内转换和随后心律失常的风险较高的患者,为临床决策提供信息.
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