肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 和COVID-19:有没有联系?
Suha AlMuhaissen1, Amal Abu Libdeh2,3, Yara ElKhatib1
1Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy, The University of Jordan, Amman, Jordan.
一项研究发现,8.1%的COVID-19幸存者符合肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 的标准. 这表明COVID-19感染和ME/CFS发展之间存在重要联系,需要进一步调查和对患者进行随访.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 是一种复杂的系统性疾病,影响神经,免疫和代谢功能.
- COVID-19的症状与ME/CFS的症状重叠,引发了人们对病毒后后果的担忧.
- 了解COVID-19后的ME/CFS患病率对于患者管理和公共卫生至关重要.
研究的目的:
- 为了确定COVID-19感染后个体中ME/CFS的流行率.
- 评估COVID-19急性和长期症状与ME/CFS诊断之间的关系.
- 调查COVID-19引发或加剧ME/CFS的可能性.
主要方法:
- 对437名确诊COVID-19的参与者进行了横截面调查问卷.
- 调查问卷是基于医学研究所 (IOM) 针对ME/CFS的临床诊断标准.
- 参与者是成年人 (18岁以上) 的BMI低于40kg/m2.
主要成果:
- 8.1%的参与者符合ME/CFS的诊断标准.
- 2.8%的参与者被归类为患有与COVID-19相关的ME/CFS.
- 其他发现包括4.6%患有与疾病相关的疲劳,0.7%患有与COVID-19无关的ME/CFS,3.7%患有长期COVID-19. 值得注意的是,近四分之一的人有ME/CFS的家族病史.
结论:
- 这项研究提供了支持COVID-19感染和ME/CFS发展之间的联系的证据.
- 在这个COVID-19后的队列中,ME/CFS的患病率与之前报告的患病率相当或略高.
- 强烈建议在COVID-19患者中密切监测和管理ME/CFS症状.
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