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儿科短肠综合征中肠道高氧流的频率和影响:一个回顾性单中心研究
Jan Thomas Schaefer1,2, Susanne Schulz-Heise3, Aline Rueckel1
1Department of Paediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Frontiers in pediatrics
|July 28, 2023
概括
肠道高氧化症影响了超过一半的儿科短肠综合征患者,导致脏问题,如结石和功能不全. 早期查和干预对于管理这种并发症至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 腎臟病學 (nephrology) 是一種醫學.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 在儿童中,短肠综合征的生存率有所改善.
- 肠道高氧化尿是短肠综合征的一个未被充分解决的并发症.
- 它可以导致结石病,结石病和功能不全.
研究的目的:
- 评估小儿短肠综合征患者肠道高氧流的患病率.
- 在这个队列中调查肠道高氧化尿的致病后果.
主要方法:
- 对患有短肠综合征的儿科患者的一项回顾性单中心研究 (2010-2022年).
- 分析了26名患者的氧酸盐分泌量,脏参数 (EGFR,结石/结石) 和临床数据.
- 还评估了短肠综合征和肠道长度的病因.
主要成果:
- 在54% (14/26) 的患者中检测到高氧.
- 4名患者发生了脏结症,3名患者证实有高氧.
- 一名患者由于高氧而患上末期病;80%的卷发患者患有肠道高氧.
结论:
- 肠道高氧化症是儿科短肠综合征的一个显著并发症,影响大约50%的患者.
- 对于这些患者,建议定期查高氧.
- 预防,包括饮食建议,可能是必要的,以防止并发症.
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