在ICU的HIN1肺炎的流行病学和结果
Vinya Golagana1, Ramesh Venkataraman2, Ashwin K Mani3
1Department of Critical Care Medicine, Apollo Hospitals, Hyderabad, Telangana, India.
概括
流行性流感A (H1N1) 肺炎经常需要在ICU中进行密集的呼吸支持. 奈的H1N1患者的结果显示,对通风和救援疗法的需求很大,死亡率与西方国家相比.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 全球范围内,H1N1/09流行性流感已经造成了显著的发病率和死亡率.
- 增加的病例需要先进的呼吸支持,突出需要了解临床过程和重症监护室 (ICU) 的结果.
研究的目的:
- 评估在奈的多学科重症监护室住院的A型流感 (H1N1) 患者的临床过程和结果.
- 评估对H1N1肺炎患者的呼吸辅助和救援疗法的使用要求.
主要方法:
- 进行了一项综合的回顾性和前性观察性研究.
- 分析了2018年10月1日至2019年1月31日期间在奈的三个ICU接受治疗的154名患者的数据.
- 记录了人口统计,风险因素,临床疗程和28天死亡率.
主要成果:
- 患者的平均年龄为58.2岁,59.1%为男性.
- 41.6%的患者需要机械通风,33.1%需要非侵入性通风或高流量鼻腔管 (HFNC).
- 采用了救援疗法,如proning (26.6%),吸入氧化 (iNO) (14.1%) 和体外膜氧化 (ECMO) (6.3%);整体28天死亡率为20.1%.
结论:
- 进入ICU的大量H1N1患者需要高水平的呼吸支持.
- 部署救援疗法是常见的,整体死亡率与西方国家相似.
- 这些发现强调了严重的H1N1肺炎的急性护理需求.
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