在6-12个月大的健康婴儿中,葡萄糖的变化
Michael Hauschild1, Cathriona Monnard2, Alison L Eldridge2
1Pediatric Endocrinology, Diabetes and Obesity Unit, Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Frontiers in nutrition
|July 28, 2023
概括
持续葡萄糖监测 (CGM) 是可行的,用于跟踪婴儿在补充养期间的葡萄糖水平. 高碳水化合物食显著影响葡萄糖的变化,这表明饮食对婴儿代谢健康的影响.
科学领域:
- 儿童营养学 儿童营养学
- 代谢健康 代谢健康
- 婴儿发育 婴儿发育
背景情况:
- 在最初的1000天内代谢编程会影响终身健康.
- 持续葡萄糖监测 (CGM) 可以评估饮食对婴儿葡萄糖节律的影响.
- 在补充养期间的婴儿新陈代谢对于长期的健康至关重要.
研究的目的:
- 评估CGM在6-12个月龄的婴儿中的可行性.
- 量化对婴儿食的反应中的葡萄糖变化.
- 评估宏观营养素组成和葡萄糖变化之间的关联.
主要方法:
- 在10名健康婴儿 (6-12个月) 上使用了FreeStyle Libre Pro® CGM设备.
- 在三天内收集了关于食物摄入,食时间和睡眠模式的数据.
- 采用描述性统计和混合线性模型来分析血糖变化.
主要成果:
- 与较低碳水化合物食 (≤25g) 相比,高碳水化合物食 (>30g) 诱导了较大的葡萄糖外流 (iAUC).
- 牛奶料中的脂肪含量更高 (约. 9g) 延长了达到最大葡萄糖 (Tmax) 的时间.
- 观察到葡萄糖水平在白天有显著的变化,在整个白天增加葡萄糖 (C0) 的显著变化.
结论:
- 在6-12个月的婴儿年龄组中,CGM是测量婴儿葡萄糖的可行工具.
- 观察到的日间葡萄糖变化和典型的葡萄糖值为未来的研究提供了洞察力.
- 这些发现支持进一步调查早期的营养摄入量和代谢适应.
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