腹腔皮GABA和谷氨酸神经元通过明显调节VTA细胞类型来驱动接近和避免
Lauren Faget1,2, Lucie Oriol1, Wen-Chun Lee1
1Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA.
bioRxiv : the preprint server for biology
|July 28, 2023
概括
腹部皮 (VP) 使用不同的GABA和谷氨酸神经元通过腹部体区域 (VTA) 控制行为. 这些通路调节多巴胺 (DA) 和其他神经元活动,塑造接近和避免反应.
科学领域:
- 神经科学是一个神经科学.
- 行为神经科学 行为神经科学
- 细胞神经科学 细胞神经科学
背景情况:
- 腹皮 (VP) 投射到腹膜区域 (VTA),影响接近和避开行为.
- 了解VP-VTA投射的细胞类型特定机制对于破译行为控制至关重要.
结论:
- 异质的VP细胞类型差异地参与VTA细胞类型来编排复杂的接近和避免行为.
- 将VP投射到VTA提供了一个激励行为关键电路.
- 细胞类型特定的VP-VTA通路提供了对奖励和厌恶的神经基础的见解.
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