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患有神经性厌食症和避免/限制性食物摄入障碍的患者的维生素D和低血症:一个病例对照研究
Meredith R Kells1, Chloe Roske2, Ashlie Watters3
1University of Rochester.
Research square
|July 28, 2023
概括
重新食低度症 (RH) 影响了超过三分之一的精神性厌食症 (AN) 或避免/限制性食物摄入障碍 (ARFID) 患者. 维生素D水平可以缓和重量和含量之间的关系在再养期间.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 饮食障碍 饮食障碍 饮食障碍 饮食障碍
背景情况:
- 再养低血症 (RH) 是营养康复期间常见的并发症营养不良的个人.
- 神经性厌食症 (AN) 和避免/限制性食物摄入障碍 (ARFID) 患者可能缺乏维生素D,影响的吸收.
- 在AN和ARFID群体中,维生素D状况与RH之间的特定联系尚未得到充分证实.
研究的目的:
- 为了确定低血清25-基维生素D和RH在AN和ARFID的个体中的患病率.
- 审查现有的文献,查看水平与RH危险因素之间的关联.
- 在AN和ARFID患者中研究25-基维生素D水平和血清极点之间的关系.
主要方法:
- 对307名被诊断为AN或ARFID的患者进行了回顾性图表审查,这些患者被录取到ACUTE饮食障碍和严重营养不良中心.
- 收集的数据包括入院实验室值 (维生素D,代谢面板,葡萄糖),人体测量 (体重,BMI,IBW%),年龄,疾病持续时间,养方法和血清极值.
- 统计分析包括相关性 (Pearson,Spearman),ANOVA和回归来评估与血清的变量关系.
主要成果:
- 超过三分之一 (35.3%) 的样本显示血清含量≤2.9 mg/dL,表明低度.
- 低度血的患病率在ARFID中为44%,在AN中为33%,在极点上没有显著的群体差异.
- 纳迪尔与体重,BMI,%IBW,和有积极的联系,与停留时间,血红蛋白和输液管养时间有负面联系. 较高的25-基维生素D水平减轻了最低值和入院体重之间的关联.
结论:
- 患有ARFID的个体在维生素D和RH方面表现出类似的营养脆弱性,与患有AN的人一样.
- 一个潜在的负反循环,涉及维生素D在稳定中的,可能有助于RH在AN和ARFID的发展.
- 维生素D的状况是影响饮食障碍群体在重新养期间含量的重要因素.
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