大型柱子子为Myxococcus xanthus IV型柱子提供了独特的结构和机械特性
bioRxiv : the preprint server for biology
|July 28, 2023
概括
在Myxococcus xanthus型IV pili (T4P) 中的大型主要pilin产生了刚性结构,增强了细菌的运动性和在各种表面上的粘附性. 这种刚性扩大了T4P系统的功能环境.
科学领域:
- 微生物学 微生物学
- 结构生物学 结构生物学
- 生物物理学的生物物理.
背景情况:
- 第四类 pili (T4P) 是关键的细菌附属物,参与运动,粘附,DNA吸收和生物膜形成.
- 主构成了T4P的大部分,具有保留的N端域和可变的C端域.
结论:
- 增加的T4PMx的刚性可以增强细菌在不同硬度的表面上的移动性.
- 破坏子单元间接口会降低T4PMx的刚性和运动性.
- 大型主要支柱是一种进化适应,使T4P能够在各种环境条件下发挥作用.
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