相关实验视频

Updated: Jul 21, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

在严重化的冠状动脉中,支架和扩张后的负载共享特征

Pengfei Dong¹, Jose Colmenarez¹, Juhwan Lee²

¹Florida Institute of Technology.

Research square

|July 28, 2023

概括

在化动脉中的支架显示了狗骨的形状,与非化动脉不同. 更高的膨胀压力改善了化病变中的支架扩张,支持高压气球的使用.

科学领域:

心血管研究的心血管研究.
生物医学工程生物医学工程
医疗器械技术医疗器械技术

背景情况:

支架对于治疗冠状动脉疾病至关重要.
化病变对支架的部署和有效性构成独特的挑战.
了解支架时的机械力对于最佳结果至关重要.

研究的目的:

量化支架扩张和负载转移在非化与严重化的冠状动脉.
评估在不同类型的病变中扩张后疗法的疗效.
调查膨胀压力对支架部署和化病变中的组织力学的影响.

主要方法:

在支架时对直径-压力关系的定量分析.
在气球,支架和动脉之间进行负载转移和负载共享分析.
在不同膨胀压力下,组织力学和支架形状变化的表征.

主要成果:

支架扩张在非化的病变中是圆柱形的,在严重化的病变中是狗骨形状的.
与非化 (1.4 N) 相比,向严重化的病变 (19 N) 转移的压力负荷显著更多.
增加的膨胀压力 (10-20 atm) 在化病变中改善了最小的光线直径,应力和应变能量,表明可能发生骨折.

结论:

支架部署机制在非化和严重化的冠状动脉之间存在显著差异.
较高的通胀压力有效地改善了化病变中的支架扩张,特别是当观察到狗骨形状时.
研究结果支持使用高压气球用于化病变的扩张后,平衡有效性与气球破裂的风险.

更多相关视频

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

Published on: November 19, 2020

Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease

Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease

Published on: February 18, 2020

相关概念视频

Coronary Artery Disease V: Interprofessional Care

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...