临床影响和风险因素中枢线相关的血流感染:一个系统的审查
Khadejah M Alshahrani1, Afnan Z Alhuwaishel2, Norah M Alangari1
1Department of Internal Medicine, Aseer Central Hospital, Abha, SAU.
Cureus
|July 28, 2023
概括
中线相关血流感染 (CLABSI) 是严重的医疗相关感染. 识别诸如多透导管和长时间导管等危险因素对于预防和降低患者发病率和医疗保健成本至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 医疗卫生流行病学 流行病学
- 临床医学 临床医学
背景情况:
- 中线相关血流感染 (CLABSI) 是一个重要的医疗相关感染,导致发病率和死亡率.
- CLABSI定义涉及之前使用中央线路的血流感染,不包括其他感染源.
研究的目的:
- 系统地审查与CLABSI相关的风险因素和临床影响变量.
- 综合当前关于CLABSI相关预测因素,发病率,死亡率,医疗保健费用和住院时间的证据.
主要方法:
- 对过去13年内发表的研究进行系统审查.
- 使用关键词搜索了PubMed/Medline,Google Scholar和Science Direct:CLABSI,中线相关的血液感染,风险因素,预测因素,发病率,死亡率,医疗费用,住院时间.
- 使用修改后的纽卡斯尔-太华尺度 (NOS) 来评估观察性研究的质量.
主要成果:
- 涉及32,198名参与者的15篇文章 (2010-2023) 符合纳入标准.
- 已确定的危险因素包括多透导管,多重中央静脉导管,血液恶性瘤,延长的导管,手术复杂性,延长的ICU停留时间和亲肠营养.
- 研究质量很好,偏差风险低.
结论:
- 在放置中央静脉装置之前,必须仔细考虑个别风险因素.
- 评估风险因素有助于预防CLABSI,减轻严重的临床后果,并减少相关的医疗保健费用.
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