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使用CAM-ICU-7尺度进行肝移植后痴呆症评估:一个队列分析

Filipe S Cardoso^1,2, Beverley Kok², Victor Dong³

¹Intensive Care Unit and Transplant Unit, Curry Cabral Hospital, Nova Medical School, Nova University, Lisbon, Portugal.

Canadian liver journal

|July 28, 2023

概括

使用混评估方法 (CAM) -重症监护室 (ICU) -7级别评估的 Delirium 影响了四分之一的肝移植患者. 移植后狂妄症在第3天增加了医院死亡风险.

科学领域:

肝病学肝病学是一种肝病学.
关键护理医学关键护理医学
神经科学是一个神经科学.

背景情况:

肝移植 (LT) 患者容易发生妄想症.
混评估方法 (CAM) -重症监护室 (ICU) -7尺度用于评估妄想.
在LT接受者的狂妄症评估对于结果至关重要.

研究的目的:

调查肝移植患者 Delirium 的发生率和结果.
评估痴呆症和LT后医院死亡率之间的关联.

主要方法:

一个回顾性队列研究,对150名肝移植患者进行了回顾性队列研究,这些患者被接收到ICU.
在LT后的1日和3日使用CAM-ICU-7尺度评估狂妄症.
主要终点:医院死亡率. 二级终点:住院时间.

主要成果:

痴呆症在LT后的第一天被诊断为25.3%,在LT后的第三天被诊断为27.4%.
在LT后的第3天妄与显著更高的医院死亡率有关 (11.5%与0%,p=0.019).
调整后的分析显示,在LT后的第3天妄症增加了医院死亡率 (aOR1.89). 血清肌素预测了 Delirium 的发生.

结论:

在CAM-ICU-7尺度上,大约四分之一的肝移植接受者发现了痴呆症.
在LT后的第3天发生的 Delirium 是增加医院死亡率的重要预测因素.

关键词:

混混混混混混混妄想妄想妄想妄想妄想肝功能衰竭肝功能衰竭肝功能衰竭移植移植移植移植

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