飞行前低氧症挑战测试在支气管肺形症
Jonathan C Levin1,2, Catherine A Sheils2, Lystra P Hayden2,3
1Division of Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts.
患有支气管肺功能障碍症 (BPD) 的儿童可能需要高度模拟测试,直到24个月更正妊娠年龄 (CGA). 需要呼吸支的婴儿或患有肺高血压的婴儿可能需要更长时间的测试.
科学领域:
- 儿科肺病学 儿科肺病学
- 新生儿医学 新生儿医学
- 航空航天医学 航空航天医学
背景情况:
- 患有支气管肺张力症 (BPD) 的婴儿在航空旅行中面临低氧血症的风险.
- 这些风险降低的年龄尚未确定的.
研究的目的:
- 根据BPD儿童年龄,确定高空模拟测试 (HAST) 的通过率.
- 为了确定与HAST失败相关的风险因素.
主要方法:
- 追溯分析了94项HAST研究中的63名患有BPD的儿童.
- 使用间隔审查来估计通过HAST.的时间到事件曲线.
- 通过标准包括Spo2≥90%或≥94%的肺高血压 (PH).
主要成果:
- 总的来说,63%的HAST研究都通过了.
- 在24个月的修正妊娠年龄 (CGA) 时,85%的受试者通过了HAST.
- 与延迟死亡相关的因素包括产后使用皮质类固醇,NICU排放与呼吸辅助,和气管切除术.
结论:
- 患有BPD的儿童在36周接受呼吸支,需要在至少24个月CGA之前考虑HAST.
- 对于那些有PH病史或在呼吸辅助上从NICU出院的人来说,建议进行扩展的HAST评估.
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