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Updated: Jul 21, 2025

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
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在胰腺不充分囊性纤维化中维护β细胞功能,使用高效的CFTR调节器治疗

Anneliese J Flatt1, Saba Sheikh2, Amy J Peleckis1

  • 1Division of Endocrinology, Diabetes & Metabolism, Department of Medicine and Institute for Diabetes, Obesity & Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

The Journal of clinical endocrinology and metabolism
|July 28, 2023
PubMed
概括

在囊性纤维化患者中,elexacaftor/tezacaftor/ivacaftor (ETI) 能够保持胰腺β细胞的功能. 与未经治疗的对照组不同,ETI改善了胰岛素分泌和亲胰岛素处理.

关键词:
囊性纤维化转膜导电性调节器囊性纤维化相关的糖尿病高效的调节器疗法是非常有效的.胰岛素分泌的胰岛素分泌.β细胞的分泌能力

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