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Updated: Jul 21, 2025

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描述细胞染色体P450误解变异在恒星等位基因定义中的综合效应

Nhlamulo Khoza1,2, David Twesigomwe1, Houcemeddine Othman1,3

  • 1Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, 9 Jubilee Road, Parktown, Johannesburg, 2193, South Africa.

Pharmacogenomics
|July 28, 2023
PubMed
概括

药物代谢酶的遗传变异,如细胞染色体P450 (CYP),会影响药物反应. 这项研究使用了多尺度建模,以了解CYP明星等位基因中的组合遗传变异如何影响蛋白质结构和功能.

关键词:
在此之前,CYP CYP在PharmVar中使用PharmVar.错误的意义变体的变体多尺度建模模型的使用.药物基因组学 药物基因组学恒星的等位基因 恒星的等位基因

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