左心房功能的应力测量与心力衰竭恶化的关系
Davide Diomede1, Erica Terazzi1, Nicolangelo Diomede1
1School of Cardiology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Echocardiography (Mount Kisco, N.Y.)
|July 28, 2023
概括
使用二维斑点跟踪 (2D-STE) 的左心房应变分析可以预测慢性心力衰竭 (CHF) 的恶化. 结合LA储菌株与多普勒测量透静功能,可以提高心力衰竭事件的预测准确度.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 心脏衰竭研究研究
背景情况:
- 两维斑点跟踪回声心脏图 (2D-STE) 通过变形分析和扩张功能测量来评估心房功能.
- 左心房 (LA) 功能在心力衰竭的复杂病理生理学中起作用.
研究的目的:
- 调查LA菌株参数对慢性心力衰竭 (CHF) 恶化的预测值.
- 为了确定LA菌株与扩张功能测量相结合是否可以提高心脏不良事件的预测.
主要方法:
- 患有慢性心力衰竭的门诊患者接受了心声扫描,包括使用2D-STE进行LA应变评估 (水库,管道,收缩阶段).
- 计算了各种LA延展比率和E/e'比率.
- 对患者进行了跟踪,以了解与心力衰竭恶化相关的事件.
主要成果:
- 在211名患者的队列中,37名患者在随访期间经历了心力衰竭恶化的事件.
- 多变量分析确定了LA储备菌株 (LAr),LA收缩菌株 (LAct),E/LAr,LAr/Ees和LAr/Eem作为独立的预测因素.
- 一个包含LAr < 18%,LAct > -10.0%,LAr/Ees < 1.28和E/LAr > 3.70的预测模型显示了显著的重新分类改进.
结论:
- 通过2D-STE测量的LA储和收缩应变独立地与CHF患者的心力衰竭恶化有关.
- 结合LA储菌株与多普勒测量静脉功能,可显著改善心力衰竭事件的预测.
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