怀孕前期的母亲视网膜动脉狭窄和整个怀孕期间的胎儿生长:一个前性队列研究
Ling-Jun Li1,2,3,4, Ruochen Du5, Jerry Kok Yen Chan6,7
1Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
概括
怀孕前母亲视网膜动脉狭窄与胎儿尺寸较小有关. 视网膜中较窄的血管与妊娠期间减少的腹周和股骨长度相关.
科学领域:
- 眼科医生 眼科 眼科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 周围生理学 周围生理学
背景情况:
- 怀孕前的母亲健康对胎儿发育至关重要.
- 视网膜微血管结构可能反映系统性血管健康.
研究的目的:
- 调查孕前母亲视网膜动脉口径与胎儿生长之间的关联.
- 为了确定视网膜血管口径是否预测胎儿生物识别.
主要方法:
- 对369名女性进行前性队列研究.
- 视网膜成像在怀孕前访问时进行.
- 胎儿生长生物识别 (AC,HC,FL) 在整个怀孕期间使用INTERGROWTH-21st图表进行跟踪.
主要成果:
- 在整个怀孕期间,通用视网膜动脉狭窄与胎儿腹周 (AC) z分数的减少有关.
- 收窄的视网膜动脉与AC和大腿长度 (FL) 的减少相关,z得分在怀孕24-28周和32-34周之间发生变化.
结论:
- 怀孕前的孕产妇视网膜动脉口径与胎儿的生长有关.
- 更窄的视网膜动脉体表明胎儿尺寸较小,特别是在AC和FL.
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