拉丁美洲的艺术:拉丁美洲注册,2020年
Fernando Zegers-Hochschild1,2, Javier A Crosby1,3, Carolina Musri1,3
1Unit of Reproductive Medicine, Clínica Las Condes, Santiago, Chile.
JBRA assisted reproduction
|July 28, 2023
概括
拉丁美洲的辅助生殖技术 (ART) 在2020年显示出不同的利用率和有效性. 冷胚胎移植和植入前遗传测试改善了结果,而单个胚胎移植减少了多胎和相关风险.
科学领域:
- 生殖医学 生殖医学
- 不孕症治疗 不孕症治疗
- 公共卫生 公共卫生
背景情况:
- 辅助生殖技术 (ART) 对于全球管理不孕症至关重要.
- 了解ART使用,有效性和安全性的区域差异对于改善患者护理和资源配置至关重要.
- 拉丁美洲为ART分析提供了一个独特的人口和医疗保健景观.
研究的目的:
- 评估2020年在拉丁美洲的ART的利用,有效性和安全性.
- 确定患者人口统计,治疗方案和结果的趋势.
- 为该地区基于证据的生殖决策提供数据驱动的见解.
主要方法:
- 来自拉丁美洲16个国家的188个机构的跨国数据的回顾性分析.
- 从2020年开始,包括87,732个启动的ART周期.
- 对分娩率,出生率,多胎,围产死亡率和影响结果的因素的统计分析.
主要成果:
- 巴西,墨西哥和阿根廷是ART循环的主要贡献者. 乌拉圭,阿根廷和巴拿马的人均使用率最高.
- 40岁及以上的女性占ART使用者的很大一部分 (34%).
- 冷胚胎移植 (FET) 显示出更高的分娩率 (29.0%) 比新鲜移植 (23.9%). 单个胚胎移植 (SET) 减少了多胎 (1%在eSET和30.5%在eDET) 和相关的围产死亡率.
- 植入前遗传检测 (PGT) 改善了分娩率,减少了流产率.
- 子宫内膜异位症治疗对35-40岁及40岁以上妇女的分娩率产生了积极的影响.
结论:
- 在南南合作框架内,大数据分析促进了区域在ART的增长.
- 根据这些数据实施基于证据的生殖决策可以优化ART结果.
- 调查结果强调了FET,SET和PGT的战略使用对于改善拉丁美洲的ART安全性和有效性的重要性.
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