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Updated: Jun 19, 2026

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Published on: February 3, 2008

基于纸张的微流体分析装置 (μPAD) 在法医和临床毒理学中的应用:一篇评论

Giacomo Musile¹, Cristian Grazioli², Stefano Fornasaro³

¹Unit of Forensic Medicine, Department of Diagnostics and Public Health, University of Verona, P.le Scuro 10, 37134 Verona, Italy.

|July 28, 2023

概括

基于纸质的微流体分析装置 (μPADs) 提供快速,经济高效的毒素和药物的检测,用于需要的毒理学. 这些进步正在改变法医和临床分析,未来的潜力在于可穿戴传感器.

科学领域:

分析化学分析化学
材料科学材料科学材料科学
法医毒理学法医毒理学

背景情况:

在中毒病例中,对快速的现场分析结果的需求需要具有成本效益的,用户友好的检测方法.
传统的快速测试在可访问性和检测广泛有害化合物的范围方面存在局限性.

研究的目的:

批判性地评估用于毒理学应用的纸质微流体分析装置 (μPADs) 的最新进展.
评估μPAD在法医和临床毒理学环境中的应用.
探索基于纸张的分析设备的未来前景.

主要方法:

审查基于纸张的微流体分析装置技术的最新发展.
对μPAD中用于各种分析物的检测方法的分析.
在法医和临床毒理学研究中评估μPAD性能.

主要成果:

μPAD已成功开发用于检测有毒分子,滥用药物和用于毒品犯罪的物质.
这些设备提供了一个可行的,低成本的替代传统方法的点的需求分析.
最近的研究表明,μPADs在现实世界法医和临床毒理学场景中的实用性.

结论:

基于纸质的微流体分析设备代表了快速,可访问的毒理学测试的重大进步.
未来的应用包括多传感器件,微流体分离和可穿戴传感器,以增强分析能力.
μPADs准备在毒理学中彻底改变需求点分析.

关键词:

生物传感器生物传感器临床毒理学临床毒理学毒品促成的犯罪 (DFCs)使用毒品促成的性侵犯 (DFSA)药物药物药物药物药物药物法医毒理学法医毒理学非法药物非法药物非法药物微流体学在微流体学方面纸质设备是基于纸质的设备.需要的点 (PON) 设备.这是一种有毒的毒剂.

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