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在患有眼默克尔细胞癌的患者中使用放射治疗作为有效的初级治疗方法

Marie Boileau^1,2, Manon Dubois^1,2, Henry Abi Rached^1,2

¹CHU Lille, Department of Dermatology, University of Lille, F-59000 Lille, France.

Current oncology (Toronto, Ont.)

|July 28, 2023

概括

治疗性放射治疗是一种有效和安全的治疗眼默克尔细胞癌 (MCC),特别是对于老年患者或那些不能接受手术的并发症患者. 这种方法最大限度地减少了副作用,并防止其复发.

科学领域:

在瘤学瘤学.
辐射疗法辐射疗法
眼科医生眼科眼科

背景情况:

默克尔细胞癌 (MCC) 是一种罕见的神经内分泌瘤.
眼皮MCC占所有MCC病例的2.5%. 眼皮MCC占所有MCC病例的2.5%.
由于位置或患者的并发症,眼皮MCC可能无法进行手术.

研究的目的:

评估单独使用放射治疗 (RT) 作为局部眼MCC治愈治疗的疗效和安全性.
评估RT作为MCC患者的替代方案,这些患者的手术禁忌.

主要方法:

追溯的单心研究.
11名经组织学确认的眼MCC患者接受治疗性放射治疗.
损伤剂量的中位数为57 Gy;82%接受了辅助性淋巴结辐射 (中位数为50 Gy).

主要成果:

在62个月的中位数随访期间,没有观察到与MCC相关的死亡或复发.
放射治疗的副作用是轻微的 (没有等级≥2) 和不常见的 (21%).
在患有并发症的老年患者 (平均年龄77岁) 中获得有效治疗.

结论:

治疗性放射治疗是一种有效和安全的治疗眼和周期性默克尔细胞癌.
仅仅RT提供了对手术的可行替代方案,保留了美学和功能结果.
这种方法对老年人和不适合手术的并发症患者尤其有益.

关键词:

梅克尔细胞癌瘤是什么?治疗辐射治疗辐射眼皮的眼皮眼睛的眼皮.辐射辐射辐射的辐射.利率利率利率利是什么意思皮肤癌是皮肤癌.

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