发展中的质母细胞瘤的成像谱:一个横截面观察研究
Stuart Currie1,2, Kavi Fatania3, Russell Frood3
1Department of Neuroradiology, Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Floor B, Clarendon Wing, Great George Street, Leeds LS1 3EX, UK.
Current oncology (Toronto, Ont.)
|July 28, 2023
概括
发展的质母细胞瘤 (GBM) 在其典型外观之前显示了一系列的成像变化. 早期症状包括T2高强度和CT高密度,进展到TRA GBM. 识别这些早期成像特征对于及时诊断至关重要.
科学领域:
- 神经成像是一种神经成像.
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 质母细胞瘤 (GBM) 通常呈现出一种特征性的放射性外观 (TRA),包括中心亡和外周增强.
- 在例行成像检查中在早期发育阶段检测GBM具有挑战性,但对于及时干预至关重要.
研究的目的:
- 为了研究成像变化的频谱,发生在开发质母细胞瘤之前,其典型的放射性外观.
- 为了识别早期成像特征,这些特征可能会成为非TRA GBM病变的红旗.
主要方法:
- 对2014年1月至2022年3月期间被诊断为GBM的患者的手术前成像的回顾性分析.
- 经验丰富的神经放射学家对成像进行审查,以识别和分析TRA GBM之前的模式.
- 分析损伤位置,T2信号强度,CT密度,扩散性和增强模式.
主要成果:
- 14%的GBM患者 (76/555) 之前进行了成像,其中83%的病变位于皮质/皮质下部位.
- 最早的特征包括T2高强度/CT低密度 (18病变),CT高密度 (51病变) 和T2单强度 (15病变).
- CT高密度病变显示T2单强度,减少扩散性和可变增强;从T2高密度到TRA GBM的平均时间是140天,从CT高密度到69天.
结论:
- 发展中的GBM表现出一系列的成像特征,从T2高强度/CT低密度到CT高密度和T2单强度,再到TRA GBM.
- 皮层/下皮层CT高密度/T2异常强度/低ADC病变是非TRA GBM 的红旗.
- 进一步的研究将成像发现与病理生理学联系起来,可以提高对GBM生长模式的理解.
相关概念视频
Imaging Studies I: CT and MRI
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies IV: Magnetic Resonance Imaging
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...


